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Case Study

Transforming Enterprise Collaboration for a Global Pharmaceutical Leader

A 15-month end-to-end M365 transformation — migrating 60,000+ users across three continents from legacy infrastructure to a unified cloud platform.

Ritesh Mhatre Mar 2026 12 min read
Life sciences enterprise collaboration transformation
60,000+
Mailboxes Migrated
54,000+
Collaboration Users
15 mo
Delivery Timeline
0
Critical Incidents

Our client is one of the world's leading pharmaceutical research and manufacturing organisations, operating across the United States, Europe, and Asia-Pacific. With over 60,000 global mailboxes, 54,000 collaboration users, and a tightly regulated compliance environment, their legacy messaging and telephony infrastructure had reached end-of-lifecycle.

Any disruption to communications could directly impact research, clinical operations, and regulatory workflows.

!Key Challenges

Legacy Infrastructure

Exchange 2010 & Lync 2010 approaching end-of-support across 3 regions.

Massive Scale Migration

60,000 mailboxes averaging 520 MB — phased, zero-data-loss migration required.

Federated Partners

25–30 federated partner organizations with TLS-secured connectivity.

Identity Integration

FIM identity integration required 6+ months prior to any user migration.

Enterprise Voice

29,000+ UM users with enterprise voice — zero service interruption acceptable.

Compliance Mandates

RPO 30 min & RTO 8 hours mandated by compliance team.

Insyto's Approach

M365 Readiness Assessment across all zones before any migration activity
Zone-based migration sequence (Zone 3 → 2 → 1) to minimise business risk
ADFS + DIRSync deployed for seamless SSO on laptops and iOS devices
Active/Active HA — two passive copies per active DB in every region
Zero-touch migration tooling reduced manual effort by 60%+
24x7 managed support with dedicated onsite leads from Day 1 of transition

Five Phases, One Seamless Transformation

Requirements
Build
Integration
UAT & Pilot
Migration

Business Outcomes

60,000+

Mailboxes migrated with zero data loss across US, EMEA, and APAC

RPO 30 min

Recovery Point Objective met — RTO 8 hours maintained throughout

29,000+

UM users transitioned with enterprise voice & video conferencing

60%+

Reduction in manual effort via zero-touch tooling & automation

3 Regions

US, EMEA & APAC — Active/Active HA with site resiliency

0 P2 Issues

No high-severity incidents from month 6 onward

"The complexity of migrating 60,000 users across three regions — with enterprise voice, federated partners, and a live research environment — required a partner who understood not just Microsoft technology, but pharmaceutical-grade operational risk."

— IT Director, Global Pharmaceutical Enterprise

Key Takeaway

Enterprise-scale M365 migrations in regulated industries demand zone-based execution, zero-touch automation, and pharmaceutical-grade risk management — not just technical migration skills.

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